mtDNA contamnation detection for whole genome and targed mtDNA sequencing studies.
Haplocheck is a contamination tool using the mtDNA phylogeny and has been integrated into the mitoverse mtDNA platform based on Cloudgene.
Run Haplocheck locally
Using Cloudgene, the complete workflow can also be executed locally. The final report is located
curl -s install.cloudgene.io | bash -s 2.0.0-rc9 ./cloudgene install https://github.com/genepi/haplocheck/releases/download/v1.0.2/haplocheck.zip ./cloudgene run firstname.lastname@example.org --files <input-files> --output <folder>
Input File Formats
Haplocheck accepts BAM/CRAM files, vcf.gz as an input.
Output File Formats
Haplocheck genereates a text file including summary statistics for each sample and a contamination status. It also provides a graphical report which can shared with collaborators.
Please click here to get the latest documentation.
Check out our blog regarding mtDNA topics.
cloudgene install https://github.com/genepi/haplocheck/releases/download/v1.0.4/haplocheck.zip
- Login to Clougene and open the Admin Panel
- Click on Applications / Install App from URL
- The installation dialog appears. Please enter the following information:
- A confirmation dialog appears and you can change permissions for the application